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Non-Consolidated Affiliates (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Feb. 11, 2020
May 31, 2018
Mar. 31, 2017
Schedule of Equity Method Investments [Line Items]            
Investments in non-consolidated affiliates $ 454,936 $ 124,061        
Distributions from non-consolidated affiliates 15,084 0 $ 0      
Equity in income (loss) of non-consolidated affiliates 44,459 (32,517) (7,023)      
Distributions from non-consolidated affiliates 42,334 14,059 39,402      
Avillion II | Merck Asset - Phase II Clinical Trial            
Schedule of Equity Method Investments [Line Items]            
Other commitment   19,000        
Other commitments, percentage of costs (as a percent)           50.00%
Avillion II | AZ Asset - Phase II and Phase III Clinical Trial            
Schedule of Equity Method Investments [Line Items]            
Other commitment         $ 105,000  
Other commitments, percentage of costs (as a percent)         44.00%  
Equity Method Investment, Nonconsolidated Investee or Group of Investees | Legacy Investors Partnerships            
Schedule of Equity Method Investments [Line Items]            
Investments in non-consolidated affiliates       $ 303,700    
Distributions from non-consolidated affiliates 22,700          
Equity in income (loss) of non-consolidated affiliates 62,000          
Equity Method Investment, Nonconsolidated Investee or Group of Investees | Avillion Entities            
Schedule of Equity Method Investments [Line Items]            
Equity in income (loss) of non-consolidated affiliates (17,600) (32,500) $ (7,000)      
Equity method investment, unfunded commitments 28,600 70,800        
Equity Method Investment, Nonconsolidated Investee or Group of Investees | Avillion I            
Schedule of Equity Method Investments [Line Items]            
Distributions from non-consolidated affiliates 13,400 $ 14,100        
Equity Method Investment, Nonconsolidated Investee or Group of Investees | Avillion II            
Schedule of Equity Method Investments [Line Items]            
Distributions from non-consolidated affiliates $ 21,300