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Liquidity and Capital Resources - Additional Information (Details) - USD ($)
$ in Thousands
Aug. 21, 2020
Jan. 09, 2020
Jun. 30, 2021
Dec. 31, 2020
Liquidity And Capital Resources [Line Items]        
Accumulated deficit     $ 466,692 $ 488,195
Cash and cash equivalents     $ 159,686 $ 228,631
Proceeds from issuance of common stock, net $ 135,435      
OrbiMed Royalty & Credit Opportunities, LP.        
Liquidity And Capital Resources [Line Items]        
Aggregate proceeds from loan   $ 200,000