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Debt - Additional Information (Details) - USD ($)
$ in Thousands
1 Months Ended 9 Months Ended 12 Months Ended
Jan. 09, 2020
Aug. 31, 2021
Jan. 31, 2020
Sep. 30, 2020
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Debt Instrument [Line Items]              
Debt issuance costs paid         $ 9,152 $ 5,804 $ 5,184
Loss on debt extinguishment         26,146 $ 22,639  
Senior Secured Term Loan | Blackstone Alternative Credit Advisors ("Blackstone")              
Debt Instrument [Line Items]              
Aggregate principal amount   $ 200,000          
Debt issuance costs   8,151          
Cash proceeds received   $ 191,849          
Term of loan   5 years          
Fair value of loan         185,389    
Senior Secured Term Loan | Blackstone Alternative Credit Advisors ("Blackstone") | Repayment of Debt Commencing on December 31, 2021              
Debt Instrument [Line Items]              
Periodic payment principal   $ 500          
Senior Secured Term Loan | Blackstone Alternative Credit Advisors ("Blackstone") | Repayment of Debt Beginning on March 31, 2024              
Debt Instrument [Line Items]              
Periodic payment principal   5,000          
Senior Secured Term Loan | Blackstone Alternative Credit Advisors ("Blackstone") | Repayment of Debt Due on Maturity Date              
Debt Instrument [Line Items]              
Periodic payment principal   $ 145,500          
Senior Secured Term Loan | Blackstone Alternative Credit Advisors ("Blackstone") | London Interbank Offered Rate (LIBOR) [Member]              
Debt Instrument [Line Items]              
Basis spread on variable rate   6.50%          
Senior Secured Term Loan | Blackstone Alternative Credit Advisors ("Blackstone") | London Interbank Offered Rate (LIBOR) [Member] | Minimum              
Debt Instrument [Line Items]              
Basis spread on variable rate   1.00%          
Senior Secured Delayed Draw Term Loan | Blackstone Alternative Credit Advisors ("Blackstone")              
Debt Instrument [Line Items]              
Aggregate principal amount   $ 100,000          
Debt issuance costs   $ 1,000          
Credit Agreement | OrbiMed Royalty & Credit Opportunities, LP.              
Debt Instrument [Line Items]              
Aggregate principal amount     $ 200,000        
Basis spread on variable rate     11.00%        
Term of loan 6 years            
Fixed interest rate     2.00%        
Debt instrument exit fee percentage     7.00%        
Extinguishment of loan, amount     $ 222,666        
Loss on debt extinguishment         $ 26,146    
Multi-draw Loan Agreement | CRG Servicing LLC              
Debt Instrument [Line Items]              
Aggregate principal amount     200,000        
Extinguishment of loan, amount     $ 120,893        
Loss on debt extinguishment       $ 22,639