Goodwill and Intangible Assets - Intangible Assets (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Goodwill and Intangible Assets
Gross amount of amortizable intangible assets	$ 27,700	$ 27,800
Accumulated amortization of intangible assets	15,900	14,200
Increase (Decrease) in intangible assets due to foreign currency translation adjustments	(197)	67
Impairment of indefinite-lived intangible assets in-process research and development project	55
Estimated annual amortization expense, intangible assets, 2022	2,100
Estimated annual amortization expense, intangible assets, 2023	2,000
Estimated annual amortization expense, intangible assets, 2024	1,900
Estimated annual amortization expense, intangible assets, 2025	1,700
Estimated annual amortization expense, intangible assets, 2025	1,600
Indefinite-lived intangible assets related to in-process R&D acquired in a business combination	919	1,200
Walk Vascular, LLC
Goodwill and Intangible Assets
Indefinite-lived intangible assets acquired	80
Amortizable intangible assets acquired	$ 120
Amortization period of intangible assets	9 years
Established Pharmaceutical Products Segment
Goodwill and Intangible Assets
Impairment of amortizable intangible assets	$ 14
Medical Devices
Goodwill and Intangible Assets
Impairment of amortizable intangible assets		$ 148
Minimum
Goodwill and Intangible Assets
Amortization period of intangible assets	2 years
Maximum
Goodwill and Intangible Assets
Amortization period of intangible assets	20 years