UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 14A

Proxy Statement Pursuant to Section 14(a) of the

Securities Exchange Act of 1934

(Amendment No.     )

Filed by the Registrant  ☒

Filed by a Party other than the Registrant  ☐

Check the appropriate box:

☐ Preliminary Proxy Statement

☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

☐ Definitive Proxy Statement

☒ Definitive Additional Materials

☐ Soliciting Material under §240.14a-12

Vincerx Pharma, Inc.

(Name of Registrant as Specified In Its Charter)

(Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check all boxes that apply):

☒ No fee required.

☐ Fee paid previously with preliminary materials.

☐ Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11.

	You May Vote Your Proxy When You View The Material On The Internet. You Will Be Asked To Follow The Prompts To Vote Your Shares.
VINCERX PHARMA, INC.	Vincerx Pharma, Inc.
c/o Continental Proxy Services 1 State Street, New York NY 10004	260 Sheridan Avenue, Suite 400 Palo Alto, CA 94306
	NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
	to be held on
	Thursday, May 25, 2023

*Stockholders are cordially invited to attend the Virtual Annual Meeting and to vote on the Internet or any Mobile device.

Dear Stockholder,

The 2023 Annual Meeting of Stockholders of Vincerx Pharma, Inc. will be conducted virtually over the Internet. You will be able to attend the 2023 Annual Meeting, vote your shares electronically and submit your questions during the live webcast of the meeting being held on Thursday, May 25, 2023, at 10:00 AM (Pacific Time) by visiting https://www.cstproxy.com/vincerx/2023.

Proposals to be considered at the 2023 Annual Meeting:

(1) To elect two Class III directors to serve until the 2026 annual meeting of stockholders or until their successors are duly elected and qualified; and

(2) To ratify the appointment of WithumSmith+Brown, PC as our independent registered public accounting firm for the year ending December 31, 2023.

The Board of Directors recommends a vote “FOR all nominees” under Proposal 1 and “FOR” Proposal 2.

NOTE: In his or her discretion, the proxies are authorized to vote upon and transact such other business as may properly come before the meeting or any adjournment thereof.

Your electronic vote authorizes the named proxies to vote your shares in the same

manner as if you marked, signed, dated, and returned the proxy card.

    Vote during the Meeting –   If you plan to attend the virtual online annual meeting, you will need your 12 digit control number to vote electronically during the annual meeting. To attend the annual meeting, visit: https://www.cstproxy.com/vincerx/2023       Vote Your Proxy on the Internet:   Go to http://www.cstproxyvote.com Have your notice available when you access the above website. Follow the prompts to vote your shares.

	CONTROL NUMBER
The Proxy Materials are available for review at:
https://www.cstproxy.com/vincerx/2023

Vincerx Pharma, Inc.

260 Sheridan Avenue, Suite 400

Palo Alto, CA 94306

Important Notice Regarding the Availability of Proxy Materials

For the 2023 Annual Meeting of Stockholders to be Held on May 25, 2023

The following Proxy Materials are available to you to review at: https://www.cstproxy.com/vincerx/2023

- the Company’s Annual Report for the year ended December 31, 2022;

- the Company’s 2023 Proxy Statement;

- the Proxy Card; and

- any amendments to the foregoing materials that are required to be furnished to stockholders.

This is not a ballot. You cannot use this notice to vote your shares. This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. We encourage you to access and review all of the important information contained in the proxy materials before voting.

If you would like to receive a paper or e-mail copy of these documents, you must request one. There is no charge for such documents to be mailed to you. Please make your request for a copy as instructed below on or before May 11, 2023 to facilitate a timely delivery. You may also request that you receive paper copies of all future proxy materials from the Company.

ACCESSING YOUR PROXY MATERIALS ONLINE

Have this notice available when you request a paper copy

of the proxy materials or to vote your proxy electronically.

You must reference your Control number.

REQUESTING A PAPER COPY OF THE PROXY MATERIALS

By telephone please call 1-888-266-6791, or

By logging on to https://www.cstproxy.com/vincerx/2023 or

By email at: proxy@continentalstock.com

Please include the company name and your control number in the subject line.