CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023
Operating activities:
Net loss	$ (119,928)	$ (129,538)
Adjustments to reconcile net loss to net cash used in operating activities:
Equity-based compensation expense	28,190	22,919
Accretion on marketable securities	(11,958)	(6,533)
Depreciation and amortization	229	233
Impairment of long-lived assets	0	440
Realized gain on marketable securities	0	(20)
Non-cash contributions from noncontrolling interests	0	4
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	(837)	(2,650)
Accounts payable	(378)	(1,709)
Accrued expenses and other current liabilities	(3,995)	4,992
Income tax payable	0	(4,282)
Net cash used in operating activities	(108,677)	(116,144)
Investing activities:
Purchase of marketable securities	(553,095)	(307,371)
Maturities of marketable securities	400,817	291,915
Purchase of property and equipment	0	(208)
Net cash used in investing activities	(152,278)	(15,664)
Financing activities:
Issuance of common stock and pre-funded warrants, net of issuance costs	262,652	38,388
Net issuance of common stock under equity-based compensation plans	6,402	290
Acquisition of noncontrolling interests	(4,448)	0
Issuance of convertible notes	0	1,825
Net cash provided by financing activities	264,606	40,503
Net increase (decrease) in cash and cash equivalents	3,651	(91,305)
Cash and cash equivalents at beginning of period	98,434	156,152
Cash and cash equivalents at end of period	102,085	64,847
Non-cash financing activities and supplemental cash flow information
Cash paid (refunded) for income taxes	(2,274)	4,708
Conversion of convertible note into noncontrolling interest	$ 0	$ 175