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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Operating activities:    
Net income (loss) $ 136,283 $ (33,279)
Adjustments to reconcile net income (loss) to net cash used in operating activities:    
Gain on sale of Cullinan Pearl (276,785) 0
Depreciation and amortization 34 41
Equity-based compensation expense 20,444 12,230
Amortization or accretion on marketable securities 1,894 1,973
Realized loss on marketable securities 109 0
License expense in exchange for subsidiary common stock 139 67
Loss on disposal of fixed assets 14 0
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (507) (5,104)
Accounts payable (1,654) (5,980)
Accrued expenses and other current liabilities 6,950 1,790
Income tax payable 11,398 0
Net cash used in operating activities (101,681) (28,262)
Investing activities:    
Purchase of marketable securities (217,497) (448,551)
Proceeds from sales and maturities of marketable securities 220,333 130,638
Proceeds from sale of Cullinan Pearl, net cash transferred with sale of $2,898 275,000 0
Purchase of property and equipment (251) 0
Net cash provided by (used in) investing activities 277,585 (317,913)
Financing activities:    
Proceeds from initial public offering 0 267,268
Payment of deferred offering costs 0 (2,688)
Proceeds from issuance of noncontrolling interests 1,153 923
Proceeds from issuance of convertible note 2,200 0
Repayment of convertible note (2,200) 0
Proceeds from net issuance of common stock under equity-based compensation plans 5,826 579
Net cash provided by financing activities 6,979 266,082
Net increase (decrease) in cash and cash equivalents 182,883 (80,093)
Cash and cash equivalents at beginning of period 59,774 168,198
Cash and cash equivalents at end of period 242,657 88,105
Non-cash financing activities and supplemental cash flow information    
Purchases of property and equipment included in accounts payable and accrued expenses and other liabilities 513 0
Cash paid for income taxes 32,582 0
Deferred offering costs paid in the prior year $ 0 $ 65