Leases - Additional Information (Details) - USD ($) $ in Thousands	1 Months Ended						12 Months Ended
	Aug. 31, 2022	Oct. 31, 2021	Jul. 31, 2021	Jan. 31, 2021	May 31, 2020	May 31, 2018	Dec. 31, 2022	Dec. 31, 2021
Lessee Lease Description [Line Items]
Weighted-average discount rate							9.80%
Right-of-use assets obtained in exchange for operating lease liabilities resulting from new leases							$ 59,500
Right-of-use assets obtained in exchange for operating lease liabilities resulting from modifications of existing leases							18,700
Lessee, operating lease, term of contract			12 years
Cash received for tenant improvement allowances to be repaid			$ 4,400
Lease liabilities							82,934
Right-of-use assets							$ 45,749	$ 11,678
Maximum
Lessee Lease Description [Line Items]
Tenant improvement allowances yet to receive			$ 25,200
Letter of Credit
Lessee Lease Description [Line Items]
Security deposit								$ 1,600
Third amendment
Lessee Lease Description [Line Items]
Operating lease, description							The lease amendment for this additional space commenced in April 2021 and expires in March 2024.
Lease expiration month and year				2024-03
Initial Lease Agreement
Lessee Lease Description [Line Items]
Operating lease, existence of option to extend		true			true
Lease term					8 years
Lease expiration year		2029			2029
Lessee option to extend description		The lease amendment of this additional space commenced in April 2022 and expires in January 2029. The lease amendment also includes this additional space in the Company’s option to extend the amended Initial Lease Agreement for an additional seven-year term.					The lease amendment also includes an extension of the lease term for the existing office and laboratory space beginning on May 1, 2020 and expiring in January 2029. The amendment to the Initial Lease Agreement also includes an option to extend the lease for an additional seven-year term.
Second Amendment Of Additional Lease Agreement
Lessee Lease Description [Line Items]
Tenant improvement allowances yet to receive	$ 25,200
Additional tenant improvement allowances	$ 15,000
Corporate Office and Laboratory Space
Lessee Lease Description [Line Items]
Weighted-average remaining lease term							10 years 9 months 18 days
Lease expiration year						2025
Corporate Office and Laboratory Space | Initial Lease Agreement
Lessee Lease Description [Line Items]
Renewal term					7 years
Operating lease, existence of option to extend						true
Lessee option to extend description							In April 2019, the Company executed the first amendment to the Initial Lease Agreement for additional corporate space, laboratory space and manufacturing capabilities and an extension to the lease term through April 2026.