The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4D MOLECULAR THERAPEUTICS IN COM 35104E100   8,207,136 257,600 SH Put SOLE   257,600 0 0
4D MOLECULAR THERAPEUTICS IN COM 35104E100   8,207,136 257,600 SH Call SOLE   257,600 0 0
ABEONA THERAPEUTICS INC COM NEW 00289Y206   6,442,299 888,593 SH   SOLE   888,593 0 0
ABEONA THERAPEUTICS INC COM NEW 00289Y206   489,375 67,500 SH Call SOLE   67,500 0 0
ACELYRIN INC COM 00445A100   10,559,295 1,564,340 SH   SOLE   1,564,340 0 0
ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102   1,803,976 1,443,181 SH   SOLE   1,443,181 0 0
ACUMEN PHARMACEUTICALS INC COM 00509G209   1,079,063 266,435 SH   SOLE   266,435 0 0
AEON BIOPHARMA INC CL A 00791X100   2,992,534 257,977 SH   SOLE   257,977 0 0
AEROVATE THERAPEUTICS INC COM 008064107   10,880,725 367,965 SH   SOLE   367,965 0 0
ALEXANDRIA REAL ESTATE EQ IN COM 015271109   9,449,103 73,300 SH Put SOLE   73,300 0 0
ALLAKOS INC COM 01671P100   1,175,171 932,675 SH   SOLE   932,675 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   7,702,802 51,541 SH   SOLE   51,541 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   20,429,815 136,700 SH Put SOLE   136,700 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   18,053,560 120,800 SH Call SOLE   120,800 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100   10,360,508 261,365 SH   SOLE   261,365 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100   4,082,920 103,000 SH Call SOLE   103,000 0 0
AMGEN INC COM 031162100   17,059,200 60,000 SH Call SOLE   60,000 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101   941,321 331,451 SH   SOLE   331,451 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101   529,376 186,400 SH Put SOLE   186,400 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101   3,010,684 1,060,100 SH Call SOLE   1,060,100 0 0
ANEBULO PHARMACEUTICALS INC COM 034569103   453,064 157,862 SH   SOLE   157,862 0 0
ANNEXON INC COM 03589W102   10,073,850 1,405,000 SH   SOLE   1,405,000 0 0
ANNOVIS BIO INC COM 03615A108   2,997,610 251,900 SH Put SOLE   251,900 0 0
ANNOVIS BIO INC COM 03615A108   2,975,000 250,000 SH Call SOLE   250,000 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   2,062,708 35,092 SH   SOLE   35,092 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   5,878,000 100,000 SH Put SOLE   100,000 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108   5,843,352 589,642 SH   SOLE   589,642 0 0
ASLAN PHARMACEUTICALS LTD SPON ADS NEW 04522R200   6,273 35,420 SH   SOLE   35,420 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108   20,948,300 309,200 SH Call SOLE   309,200 0 0
ASTRIA THERAPEUTICS INC COM 04635X102   1,980,170 140,687 SH   SOLE   140,687 0 0
ASTRIA THERAPEUTICS INC COM 04635X102   2,163,329 153,700 SH Put SOLE   153,700 0 0
ASTRIA THERAPEUTICS INC COM 04635X102   5,630,000 400,000 SH Call SOLE   400,000 0 0
AVALO THERAPEUTICS INC COM NEW 05338F306   1,014,594 46,648 SH   SOLE   46,648 0 0
AVROBIO INC COM 05455M100   965,198 754,061 SH   SOLE   754,061 0 0
BIOHAVEN LTD COM G1110E107   12,234,153 223,700 SH Call SOLE   223,700 0 0
BIOMEA FUSION INC COM 09077A106   1,539,850 103,000 SH Put SOLE   103,000 0 0
BIOMEA FUSION INC COM 09077A106   16,110,120 1,077,600 SH Call SOLE   1,077,600 0 0
BRAINSTORM CELL THERAPEUTICS COM NEW 10501E201   50,960 90,242 SH   SOLE   90,242 0 0
BRIDGEBIO PHARMA INC COM 10806X102   8,719,842 282,013 SH   SOLE   282,013 0 0
BRIDGEBIO PHARMA INC COM 10806X102   12,040,248 389,400 SH Call SOLE   389,400 0 0
CABALETTA BIO INC COM 12674W109   3,412,000 200,000 SH Put SOLE   200,000 0 0
CATALYST PHARMACEUTICALS INC COM 14888U101   8,263,073 518,386 SH   SOLE   518,386 0 0
CERVOMED INC COM 15713L109   5,530,138 237,345 SH   SOLE   237,345 0 0
CHEMOMAB THERAPEUTICS LTD SPONSORED ADS 16385C104   166,232 213,392 SH   SOLE   213,392 0 0
CORBUS PHARMACEUTICALS HLDGS COM NEW 21833P301   21,945,794 559,271 SH   SOLE   559,271 0 0
CORCEPT THERAPEUTICS INC COM 218352102   25,051,455 994,500 SH Put SOLE   994,500 0 0
CORCEPT THERAPEUTICS INC COM 218352102   7,040,605 279,500 SH Call SOLE   279,500 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   30,133,984 643,751 SH   SOLE   643,751 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   14,061,724 300,400 SH Put SOLE   300,400 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   407,247 8,700 SH Call SOLE   8,700 0 0
CYBIN INC COM 23256X100   5,769,768 13,953,488 SH   SOLE   13,953,488 0 0
CYTOKINETICS INC COM NEW 23282W605   10,176,256 145,147 SH   SOLE   145,147 0 0
CYTOKINETICS INC COM NEW 23282W605   7,011,000 100,000 SH Put SOLE   100,000 0 0
DISC MEDICINE INC COM 254604101   1,579,660 25,372 SH   SOLE   25,372 0 0
DISC MEDICINE INC COM 254604101   24,692,316 396,600 SH Put SOLE   396,600 0 0
DISC MEDICINE INC COM 254604101   3,088,096 49,600 SH Call SOLE   49,600 0 0
ELEVATION ONCOLOGY INC COM 28623U101   759,697 148,089 SH   SOLE   148,089 0 0
EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209   21,642 1,047 SH   SOLE   1,047 0 0
EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209   13,604,994 658,200 SH Put SOLE   658,200 0 0
EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209   4,268,355 206,500 SH Call SOLE   206,500 0 0
FINCH THERAPEUTICS GROUP INC COM NEW 31773D200   18,126 6,892 SH   SOLE   6,892 0 0
GLYCOMIMETICS INC COM 38000Q102   518,400 172,800 SH Put SOLE   172,800 0 0
GLYCOMIMETICS INC COM 38000Q102   518,400 172,800 SH Call SOLE   172,800 0 0
HOOKIPA PHARMA INC COM 43906K100   377,913 530,776 SH   SOLE   530,776 0 0
IBIO INC CON NEW 451033708   2,436,000 600,000 SH   SOLE   600,000 0 0
IMMATICS N.V SHS N44445109   519,351 49,415 SH   SOLE   49,415 0 0
IMMUNIC INC COM 4525EP101   2,128,339 1,612,378 SH   SOLE   1,612,378 0 0
IMMUNOVANT INC COM 45258J102   8,947,446 276,925 SH   SOLE   276,925 0 0
INFLARX NV COM N44821101   1,085,680 704,987 SH   SOLE   704,987 0 0
INSMED INC COM PAR $.01 457669307   1,392,718 51,335 SH   SOLE   51,335 0 0
INSMED INC COM PAR $.01 457669307   1,923,517 70,900 SH Put SOLE   70,900 0 0
INSMED INC COM PAR $.01 457669307   9,419,536 347,200 SH Call SOLE   347,200 0 0
ITEOS THERAPEUTICS INC COM 46565G104   1,382,073 101,325 SH   SOLE   101,325 0 0
JASPER THERAPEUTICS INC COM NEW 471871202   3,087,939 105,175 SH   SOLE   105,175 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106   618,126 409,355 SH   SOLE   409,355 0 0
KEZAR LIFE SCIENCES INC COM 49372L100   783,484 868,992 SH   SOLE   868,992 0 0
KODIAK SCIENCES INC COM 50015M109   2,506,842 476,586 SH   SOLE   476,586 0 0
KRYSTAL BIOTECH INC COM 501147102   66,723,750 375,000 SH Put SOLE   375,000 0 0
KRYSTAL BIOTECH INC COM 501147102   17,793,000 100,000 SH Call SOLE   100,000 0 0
LANTHEUS HLDGS INC COM 516544103   10,580,800 170,000 SH Call SOLE   170,000 0 0
LARIMAR THERAPEUTICS INC COM 517125100   3,328,427 438,528 SH   SOLE   438,528 0 0
LENZ THERAPEUTICS INC COM 52635N103   1,898,050 85,000 SH   SOLE   85,000 0 0
LONGBOARD PHARMACEUTICALS IN COM 54300N103   5,098 236 SH   SOLE   236 0 0
LYRA THERAPEUTICS INC COM 55234L105   6,573,477 1,056,829 SH   SOLE   1,056,829 0 0
MACROGENICS INC COM 556099109   4,683,418 318,167 SH   SOLE   318,167 0 0
MACROGENICS INC COM 556099109   7,705,920 523,500 SH Call SOLE   523,500 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   13,725,856 51,400 SH Put SOLE   51,400 0 0
MARINUS PHARMACEUTICALS INC COM NEW 56854Q200   4,862,842 537,925 SH   SOLE   537,925 0 0
MARINUS PHARMACEUTICALS INC COM NEW 56854Q200   1,918,288 212,200 SH Put SOLE   212,200 0 0
MARINUS PHARMACEUTICALS INC COM NEW 56854Q200   2,740,928 303,200 SH Call SOLE   303,200 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107   834,174 466,019 SH   SOLE   466,019 0 0
MIND MEDICINE MINDMED INC COM NEW 60255C885   2,796,321 297,481 SH   SOLE   297,481 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104   7,936,340 158,000 SH Put SOLE   158,000 0 0
NURIX THERAPEUTICS INC COM 67080M103   4,410,000 300,000 SH   SOLE   300,000 0 0
NUVALENT INC COM 670703107   7,629,219 101,601 SH   SOLE   101,601 0 0
NUVATION BIO INC COM CL A 67080N101   2,305,146 633,282 SH   SOLE   633,282 0 0
NYXOAH S A SHS B6S7WD106   683,929 50,699 SH   SOLE   50,699 0 0
PRAXIS PRECISION MEDICINES I COM NEW 74006W207   10,275,036 168,388 SH   SOLE   168,388 0 0
PRAXIS PRECISION MEDICINES I COM NEW 74006W207   1,330,236 21,800 SH Call SOLE   21,800 0 0
PROQR THRAPEUTICS N V SHS EURO N71542109   1,097,734 483,583 SH   SOLE   483,583 0 0
PROTARA THERAPEUTICS INC COM STK 74365U107   812,830 202,701 SH   SOLE   202,701 0 0
PYXIS ONCOLOGY INC COMMON STOCK 747324101   7,081,858 1,662,408 SH   SOLE   1,662,408 0 0
Q32 BIO INC COM 746964105   380,588 22,335 SH   SOLE   22,335 0 0
RAPT THERAPEUTICS INC COM 75382E109   1,388,532 154,625 SH   SOLE   154,625 0 0
RAPT THERAPEUTICS INC COM 75382E109   2,210,876 246,200 SH Put SOLE   246,200 0 0
RAPT THERAPEUTICS INC COM 75382E109   783,056 87,200 SH Call SOLE   87,200 0 0
RELMADA THERAPEUTICS INC COM 75955J402   187,717 40,369 SH   SOLE   40,369 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106   8,003,767 297,096 SH   SOLE   297,096 0 0
ROIVANT SCIENCES LTD SHS G76279101   1,060,419 100,609 SH   SOLE   100,609 0 0
SAGIMET BIOSCIENCES INC COM SER A 786700104   2,236,103 412,565 SH   SOLE   412,565 0 0
SAREPTA THERAPEUTICS INC COM 803607100   19,713,910 152,278 SH   SOLE   152,278 0 0
SAREPTA THERAPEUTICS INC COM 803607100   15,030,306 116,100 SH Call SOLE   116,100 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103   5,180,610 291,701 SH   SOLE   291,701 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103   6,434,448 362,300 SH Call SOLE   362,300 0 0
SOLENO THERAPEUTICS INC COM 834203309   24,199,591 565,411 SH   SOLE   565,411 0 0
SOLENO THERAPEUTICS INC COM 834203309   3,471,080 81,100 SH Call SOLE   81,100 0 0
SPDR SER TR S&P BIOTECH 78464A870   66,423,000 700,000 SH Put SOLE   700,000 0 0
STOKE THERAPEUTICS INC COM 86150R107   92,017 6,816 SH   SOLE   6,816 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   5,160,344 120,400 SH Put SOLE   120,400 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   85,720 2,000 SH Call SOLE   2,000 0 0
SYNLOGIC INC COM NEW 87166L209   36,602 20,448 SH   SOLE   20,448 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103   25,818,568 710,277 SH   SOLE   710,277 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103   3,635,000 100,000 SH Call SOLE   100,000 0 0
TEMPEST THERAPEUTICS INC COM 87978U108   412,895 105,600 SH   SOLE   105,600 0 0
TERNS PHARMACEUTICALS INC COM 880881107   580,540 88,497 SH   SOLE   88,497 0 0
TOURMALINE BIO INC COM 89157D105   2,484,260 108,483 SH   SOLE   108,483 0 0
TOURMALINE BIO INC COM 89157D105   4,103,680 179,200 SH Call SOLE   179,200 0 0
TYRA BIOSCIENCES INC COM 90240B106   8,216 501 SH   SOLE   501 0 0
UNIQURE NV SHS N90064101   2,439,492 469,133 SH   SOLE   469,133 0 0
VENTYX BIOSCIENCES INC COM 92332V107   2,792,059 507,647 SH   SOLE   507,647 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106   6,038,738 375,310 SH   SOLE   375,310 0 0
VERU INC COM 92536C103   662,563 946,382 SH   SOLE   946,382 0 0
VIKING THERAPEUTICS INC COM 92686J106   16,400,000 200,000 SH Put SOLE   200,000 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   3,132,539 178,900 SH Put SOLE   178,900 0 0
VOYAGER THERAPEUTICS INC COM 92915B106   1,683,779 180,857 SH   SOLE   180,857 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105   3,640,843 590,088 SH   SOLE   590,088 0 0
XENON PHARMACEUTICALS INC COM 98420N105   4,614,400 107,187 SH   SOLE   107,187 0 0