The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABSCI CORPORATION COM 00091E109   5,822,000 1,025,000 SH   SOLE   1,025,000 0 0
AKERO THERAPEUTICS INC COM 00973Y108   1,894,500 75,000 SH Call SOLE   75,000 0 0
ALKERMES PLC SHS G01767105   2,030,250 75,000 SH   SOLE   75,000 0 0
ALNYLAM PHARMACEUTICALS INC NOTE 1.000% 9/1 02043QAB3   9,448,755 10,000,000 PRN   SOLE   10,000,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   5,978,000 40,000 SH Call SOLE   40,000 0 0
ANNOVIS BIO INC COM 03615A108   867,510 72,900 SH Put SOLE   72,900 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   9,698,700 165,000 SH   SOLE   165,000 0 0
APOGEE THERAPEUTICS INC COM 03770N101   39,344,580 592,093 SH   SOLE   592,093 0 0
ARCELLX INC COMMON STOCK 03940C100   20,865,000 300,000 SH   SOLE   300,000 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100   3,432,000 120,000 SH   SOLE   120,000 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108   1,504,545 133,500 SH   SOLE   133,500 0 0
ASTRIA THERAPEUTICS INC COM 04635X102   11,901,904 845,606 SH   SOLE   845,606 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100   21,532,500 3,375,000 SH   SOLE   3,375,000 0 0
AVALO THERAPEUTICS INC COM NEW 05338F306   217,500 10,000 SH   SOLE   10,000 0 0
AVROBIO INC COM 05455M100   896,000 700,000 SH   SOLE   700,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104   11,152,688 139,758 SH   SOLE   139,758 0 0
BEIGENE LTD SPONSORED ADR 07725L102   12,846,344 82,143 SH   SOLE   82,143 0 0
BOSTON SCIENTIFIC CORP COM 101137107   1,712,250 25,000 SH   SOLE   25,000 0 0
BRIDGEBIO PHARMA INC NOTE 2.500% 3/1 10806XAB8   18,298,257 17,000,000 PRN   SOLE   17,000,000 0 0
BRIDGEBIO PHARMA INC COM 10806X102   7,730,000 250,000 SH Call SOLE   250,000 0 0
BRIDGEBIO PHARMA INC COM 10806X102   1,546,000 50,000 SH   SOLE   50,000 0 0
CASSAVA SCIENCES INC W EXP 11/15/202 14817C115   97,524 24,200 SH   SOLE   24,200 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202   21,404,700 510,000 SH   SOLE   510,000 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   9,385,170 830,546 SH   SOLE   830,546 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128   12,681,000 300,000 SH   SOLE   300,000 0 0
COHERUS BIOSCIENCES INC NOTE 1.500% 4/1 19249HAB9   5,784,786 9,000,000 PRN   SOLE   9,000,000 0 0
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101   8,551,862 1,027,868 SH   SOLE   1,027,868 0 0
CONTEXT THERAPEUTICS INC COM 21077P108   453,767 328,817 SH   SOLE   328,817 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   22,000,700 470,000 SH   SOLE   470,000 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108   4,430,400 65,000 SH Call SOLE   65,000 0 0
CULLINAN ONCOLOGY INC COM 230031106   4,406,340 258,588 SH   SOLE   258,588 0 0
CYTOKINETICS INC COM NEW 23282W605   5,608,800 80,000 SH   SOLE   80,000 0 0
ELEVATION ONCOLOGY INC COM 28623U101   6,509,072 1,268,825 SH   SOLE   1,268,825 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108   8,377,580 164,589 SH   SOLE   164,589 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108   2,545,000 50,000 SH Call SOLE   50,000 0 0
FULCRUM THERAPEUTICS INC COM 359616109   5,195,200 550,339 SH   SOLE   550,339 0 0
FULCRUM THERAPEUTICS INC COM 359616109   2,596,000 275,000 SH Call SOLE   275,000 0 0
GERON CORP COM 374163103   8,250,000 2,500,000 SH   SOLE   2,500,000 0 0
GLYCOMIMETICS INC COM 38000Q102   426,900 142,300 SH Put SOLE   142,300 0 0
GRITSTONE BIO INC COM 39868T105   6,143,842 2,390,600 SH Put SOLE   2,390,600 0 0
GUARDANT HEALTH INC COM 40131M109   5,157,500 250,000 SH Call SOLE   250,000 0 0
HELIX ACQUISITION CORP II CL A ORD SHS G4444H101   2,587,500 250,000 SH   SOLE   250,000 0 0
IMMATICS N.V SHS N44445109   3,678,500 350,000 SH   SOLE   350,000 0 0
IMMATICS N.V W EXP 07/01/202 N44445117   486,730 187,204 SH   SOLE   187,204 0 0
IMMUNITYBIO INC COM 45256X103   3,165,078 589,400 SH Put SOLE   589,400 0 0
IMMUNOVANT INC COM 45258J102   9,208,350 285,000 SH   SOLE   285,000 0 0
IMMUNOVANT INC COM 45258J102   4,665,564 144,400 SH Call SOLE   144,400 0 0
INARI MED INC COM 45332Y109   8,396,500 175,000 SH   SOLE   175,000 0 0
INOZYME PHARMA INC COM 45790W108   20,241,696 2,642,519 SH   SOLE   2,642,519 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101   3,460,000 50,000 SH   SOLE   50,000 0 0
IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108   8,966,945 1,029,500 SH Call SOLE   1,029,500 0 0
KEZAR LIFE SCIENCES INC COM 49372L100   1,588,419 1,761,778 SH   SOLE   1,761,778 0 0
KRYSTAL BIOTECH INC COM 501147102   4,758,916 26,746 SH   SOLE   26,746 0 0
KURA ONCOLOGY INC COM 50127T109   15,581,394 730,492 SH   SOLE   730,492 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   30,709,600 115,000 SH   SOLE   115,000 0 0
MERSANA THERAPEUTICS INC COM 59045L106   4,480,000 1,000,000 SH   SOLE   1,000,000 0 0
MINERALYS THERAPEUTICS INC COM 603170101   4,233,951 327,959 SH   SOLE   327,959 0 0
MIRUM PHARMACEUTICALS INC COM 604749101   4,019,200 160,000 SH   SOLE   160,000 0 0
MODERNA INC COM 60770K107   42,624,000 400,000 SH Put SOLE   400,000 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104   3,767,250 75,000 SH   SOLE   75,000 0 0
MORPHIC HLDG INC COM 61775R105   7,920,000 225,000 SH   SOLE   225,000 0 0
NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES N62509109   6,768,630 286,200 SH   SOLE   286,200 0 0
NEWAMSTERDAM PHARMA COMPANY W EXP 11/22/202 N62509117   2,236,693 202,599 SH   SOLE   202,599 0 0
NEXTCURE INC COM 65343E108   3,030,653 1,359,037 SH   SOLE   1,359,037 0 0
NURIX THERAPEUTICS INC COM 67080M103   11,910,719 810,253 SH   SOLE   810,253 0 0
NUVALENT INC COM 670703107   11,263,500 150,000 SH   SOLE   150,000 0 0
OMEROS CORP NOTE 5.250% 2/1 682143AG7   7,632,450 10,500,000 PRN   SOLE   10,500,000 0 0
PASSAGE BIO INC COM 702712100   356,759 264,266 SH   SOLE   264,266 0 0
PERSPECTIVE THERAPEUTICS INC COM 46489V104   6,069,000 5,100,000 SH   SOLE   5,100,000 0 0
PROMIS NEUROSCIENCES INC COM NEW 74346M406   507,980 265,958 SH   SOLE   0 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   2,893,000 100,000 SH   SOLE   100,000 0 0
Q32 BIO INC COM 746964105   473,320 27,777 SH   SOLE   27,777 0 0
RAPT THERAPEUTICS INC COM 75382E109   5,182,358 577,100 SH Put SOLE   577,100 0 0
RAPT THERAPEUTICS INC COM 75382E109   538,800 60,000 SH Call SOLE   60,000 0 0
REGENXBIO INC COM 75901B107   2,317,700 110,000 SH   SOLE   110,000 0 0
REZOLUTE INC COM NEW 76200L309   4,080,000 1,600,000 SH   SOLE   1,600,000 0 0
ROCKET PHARMACEUTICALS INC W EXP 09/02/202 77313F114   22,440 75,000 SH   SOLE   75,000 0 0
ROIVANT SCIENCES LTD SHS G76279101   5,270,000 500,000 SH   SOLE   500,000 0 0
SAVARA INC COM 805111101   5,727,000 1,150,000 SH   SOLE   1,150,000 0 0
SPDR SER TR S&P BIOTECH 78464A870   66,423,000 700,000 SH Put SOLE   700,000 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107   4,922,000 100,000 SH   SOLE   100,000 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202   15,551,300 410,000 SH   SOLE   410,000 0 0
TANGO THERAPEUTICS INC COM 87583X109   1,193,176 150,274 SH   SOLE   150,274 0 0
TERNS PHARMACEUTICALS INC COM 880881107   2,952,000 450,000 SH   SOLE   450,000 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209   23,352,050 1,655,000 SH Call SOLE   1,655,000 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209   19,754,000 1,400,000 SH   SOLE   1,400,000 0 0
TOURMALINE BIO INC COM 89157D105   1,145,000 50,000 SH   SOLE   50,000 0 0
TRAVERE THERAPEUTICS INC COM 89422G107   963,750 125,000 SH   SOLE   125,000 0 0
VAXCYTE INC COM 92243G108   5,464,800 80,000 SH   SOLE   80,000 0 0
VERA THERAPEUTICS INC CL A 92337R101   20,266,400 470,000 SH   SOLE   470,000 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106   13,158,933 817,833 SH   SOLE   817,833 0 0
VIKING THERAPEUTICS INC COM 92686J106   4,100,000 50,000 SH   SOLE   50,000 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105   1,768,229 286,585 SH   SOLE   286,585 0 0
XENON PHARMACEUTICALS INC COM 98420N105   36,049,510 837,387 SH   SOLE   837,387 0 0
ZURA BIO LTD CLASS A ORD SHS G9TY5A101   1,156,523 450,009 SH   SOLE   450,009 0 0