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Convertible loans - Schedule of Interest Expense (Details)
$ in Thousands
12 Months Ended
Dec. 31, 2022
USD ($)
Facility Agreement With Deerfield Partners, L.P., Tranche One  
Debt Instrument [Line Items]  
Contractual interest expense $ 2,444
Amortization of debt discount 3,220
Total 5,664
Facility Agreement With Deerfield Partners, L.P., Tranche Two  
Debt Instrument [Line Items]  
Contractual interest expense 1,880
Amortization of debt discount 140
Total $ 2,020