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Summary of Significant Accounting Policies (Tables)
 12 Months Ended
Dec. 31, 2022
Accounting Policies [Abstract]  
Schedule of Cash and Cash Equivalents and Restricted Cash The following table provides a reconciliation of cash, cash equivalents and restricted cash reported on the consolidated balance sheets that sum to the total of the same amounts shown in the consolidated statements of cash flows (in thousands):
Year Ended December 31,
202220212020
Cash and cash equivalents$219,746 $587,447 $663,603 
Restricted cash7,607 8,626 25,041 
Total cash, cash equivalents and restricted cash$227,353 $596,073 $688,644 
Schedule of Property Plant and Equipment Depreciation is computed using the straight-line method based on the estimated useful lives of the following assets:
Useful Life (Years)
Laboratory equipment and machinery 3-5
Computer equipment2-3
Furniture and fixtures3
Leasehold improvements1-11
Property and equipment, net consisted of the following (in thousands):
December 31,
20222021
Land$36,780 $36,099 
Laboratory equipment and machinery54,658 44,189 
Computer equipment12,565 12,294 
Furniture and fixtures9,642 6,208 
Leasehold improvements91,518 67,532 
Construction in progress152,995 52,191 
Total property and equipment358,158 218,513 
Less: accumulated depreciation and amortization(68,830)(49,021)
Property and equipment, net$289,328 $169,492