Income Tax - Summary Of Major Components Of Deferred Tax Assets And Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Deferred tax assets
Net operating loss carryforwards	$ 195,953	$ 90,562
Research and development tax credits	54,117	31,908
Accruals and reserves	7,868	14,392
Lease liability	19,697	14,192
Intangibles	40,716	43,261
Stock-based compensation	12,261	6,601
Total deferred tax assets	330,612	200,916
Valuation allowance	(313,194)	(186,853)
Net deferred tax assets	17,418	14,063
Deferred tax liabilities
Fixed assets	(4,189)	(3,750)
Right-of-use assets	(13,745)	(10,388)
Total deferred tax liabilities	(17,934)	(14,138)
Net deferred tax liabilities	$ (516)	$ (75)