BIOPHYTIS S.A.

Sorbonne University—BC 9, Bâtiment A 4ème étage

4 place Jussieu

75005 Paris, France

+33 1 44 27 23 00

April 27, 2023

VIA EDGAR

United States Securities and Exchange Commission

Division of Corporate Finance

100 F Street, NE

Washington, D.C. 20549

Attention: Sean Healy

Re: Biophytis S.A. (the “Registrant”) - Request for Acceleration

Registration Statement on Form F-3

File No. 333- 271385

Ladies and Gentlemen:

Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, the Registrant hereby requests acceleration of the effective date of its Registration Statement on Form F-3 (File No. 333- 271385) (the “Registration Statement”), so that it may become effective at 5:00 p.m. Eastern Standard Time on Monday, May 1, 2023, or as soon thereafter as practicable.

The Registrant hereby authorizes Wendy Grasso of Reed Smith LLP, attorneys for the Registrant, to orally modify or withdraw this request for acceleration.

The Registrant requests that it be notified of such effectiveness by a telephone call to Wendy Grasso at (212) 549-0216.

BIOPHYTIS S.A.
By:	/s/ Stanislas Veillet
Name:	Stanislas Veillet
Title:	Chief Executive Officer and Chairman