Balance Sheet Details (Tables)

3 Months Ended

Mar. 31, 2021

Balance Sheet Related Disclosures [Abstract]

Summary of Components of Property and Equipment, Net

Property and equipment, net balances as of March 31, 2021 and December 31, 2020 consisted of the following:

(in thousands)	March 31, 2021			December 31, 2020
Research equipment	$	5,895		$	5,539
Computers and software		284			284
Office equipment and furniture		574			574
Leasehold improvements		44			44
Total		6,797			6,441
Less accumulated depreciation and amortization		(3,370	)		(3,063	)
Property and equipment, net	$	3,427		$	3,378

Schedule of Accrued Liabilities

Accrued liabilities consisted of the following as of March 31, 2021 and December 31, 2020:

(in thousands)	March 31, 2021		December 31, 2020
Accrued compensation	$	3,834	$	2,097
Cystic Fibrosis Foundation Liability (Note 9)		5,913		6,585
Singapore Economic Development Board liability		—		1,761
Current portion of operating lease liability		1,443		1,630
Current portion of long-term debt		3,125		1,250
Clinical accruals		7,217		4,067
Other accrued research and development expenses		8,268		3,249
Total	$	29,800	$	20,639