Balance Sheet Details - Schedule of Accrued Liabilities (Details) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Accrued Liabilities, Current [Abstract]
Accrued compensation	$ 4,038	$ 3,578
Cystic Fibrosis Foundation liability		2,777
Income tax payable	1,295
Current portion of operating lease liability	$ 3,884	$ 1,537
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]	Total	Total
Clinical accruals	$ 4,531	$ 8,675
Vinbiocare contractual liabilities	7,468
Other accrued research and development expenses	9,016	6,956
Total	$ 30,232	$ 23,523