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Condensed Consolidated Statements of Shareholders' Equity - USD ($)
$ in Thousands
Ordinary Shares
Additional Paid-in Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Total
Beginning balance at Dec. 31, 2021 $ 384 $ 567,637 $ (3,388) $ (218,379) $ 346,254
Beginning balance (in shares) at Dec. 31, 2021 29,579,364        
Increase (decrease) in shareholders' equity (deficit)          
Issuance of ADSs upon exercise of share options $ 1 449     450
Issuance of ADSs upon exercise of share options (in shares) 30,074        
Issuance of ADSs upon vesting of restricted share units (in shares) 35,000        
Share-based compensation expense   10,198     10,198
Foreign currency translation adjustment     920   920
Net loss       (27,564) (27,564)
Ending balance at Mar. 31, 2022 $ 385 578,284 (2,468) (245,943) 330,258
Ending balance (in shares) at Mar. 31, 2022 29,644,438        
Beginning balance at Dec. 31, 2021 $ 384 567,637 (3,388) (218,379) 346,254
Beginning balance (in shares) at Dec. 31, 2021 29,579,364        
Increase (decrease) in shareholders' equity (deficit)          
Foreign currency translation adjustment         3,916
Net loss         (82,739)
Ending balance at Sep. 30, 2022 $ 385 589,679 528 (301,118) 289,474
Ending balance (in shares) at Sep. 30, 2022 29,678,431        
Beginning balance at Mar. 31, 2022 $ 385 578,284 (2,468) (245,943) 330,258
Beginning balance (in shares) at Mar. 31, 2022 29,644,438        
Increase (decrease) in shareholders' equity (deficit)          
Issuance of ADSs upon exercise of share options   195     195
Issuance of ADSs upon exercise of share options (in shares) 21,879        
Share-based compensation expense   5,673     5,673
Foreign currency translation adjustment     2,094   2,094
Net loss       (26,828) (26,828)
Ending balance at Jun. 30, 2022 $ 385 584,152 (374) (272,771) 311,392
Ending balance (in shares) at Jun. 30, 2022 29,666,317        
Increase (decrease) in shareholders' equity (deficit)          
Issuance of ADSs upon exercise of share options   159     159
Issuance of ADSs upon exercise of share options (in shares) 12,114        
Share-based compensation expense   5,368     5,368
Foreign currency translation adjustment     902   902
Net loss       (28,347) (28,347)
Ending balance at Sep. 30, 2022 $ 385 589,679 528 (301,118) 289,474
Ending balance (in shares) at Sep. 30, 2022 29,678,431        
Beginning balance at Dec. 31, 2022 $ 387 601,105 387 (331,096) $ 270,783
Beginning balance (in shares) at Dec. 31, 2022 29,873,893       29,873,893
Increase (decrease) in shareholders' equity (deficit)          
Issuance of ADSs upon exercise of share options   1     $ 1
Issuance of ADSs upon exercise of share options (in shares) 877        
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses $ 1 2,715     2,716
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses (in shares) 100,000        
Issuance of ADSs upon vesting of restricted share units $ 1       1
Issuance of ADSs upon vesting of restricted share units (in shares) 56,988        
Share-based compensation expense   9,042     9,042
Foreign currency translation adjustment     (316)   (316)
Net loss       (39,064) (39,064)
Ending balance at Mar. 31, 2023 $ 389 612,863 71 (370,160) 243,163
Ending balance (in shares) at Mar. 31, 2023 30,031,758        
Beginning balance at Dec. 31, 2022 $ 387 601,105 387 (331,096) $ 270,783
Beginning balance (in shares) at Dec. 31, 2022 29,873,893       29,873,893
Increase (decrease) in shareholders' equity (deficit)          
Foreign currency translation adjustment         $ 2,498
Net loss         (131,565)
Ending balance at Sep. 30, 2023 $ 550 875,248 2,885 (462,661) $ 416,022
Ending balance (in shares) at Sep. 30, 2023 42,384,799       42,384,799
Beginning balance at Mar. 31, 2023 $ 389 612,863 71 (370,160) $ 243,163
Beginning balance (in shares) at Mar. 31, 2023 30,031,758        
Increase (decrease) in shareholders' equity (deficit)          
Issuance of ADSs upon exercise of share options   165     165
Issuance of ADSs upon exercise of share options (in shares) 12,389        
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses $ 7 12,120     12,127
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses (in shares) 520,000        
Issuance of ADSs upon vesting of restricted share units (in shares) 21,793        
Share-based compensation expense   8,193     8,193
Foreign currency translation adjustment     (948)   (948)
Net loss       (42,603) (42,603)
Ending balance at Jun. 30, 2023 $ 396 633,341 (877) (412,763) 220,097
Ending balance (in shares) at Jun. 30, 2023 30,585,940        
Increase (decrease) in shareholders' equity (deficit)          
Issuance of ADSs upon exercise of share options   139     139
Issuance of ADSs upon exercise of share options (in shares) 13,296        
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses $ 154 234,338     234,492
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses (in shares) 11,764,706        
Issuance of ADSs upon vesting of restricted share units (in shares) 20,857        
Share-based compensation expense   7,430     7,430
Foreign currency translation adjustment     3,762   3,762
Net loss       (49,898) (49,898)
Ending balance at Sep. 30, 2023 $ 550 $ 875,248 $ 2,885 $ (462,661) $ 416,022
Ending balance (in shares) at Sep. 30, 2023 42,384,799       42,384,799