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Condensed Consolidated Statements of Shareholders' Equity - USD ($)
$ in Thousands
Ordinary Shares
Additional Paid-in Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Total
Beginning balance at Dec. 31, 2021 $ 384 $ 567,637 $ (3,388) $ (218,379) $ 346,254
Beginning balance (in shares) at Dec. 31, 2021 29,579,364        
Increase (decrease) in shareholders' equity (deficit)          
Issuance of ADSs upon exercise of share options $ 1 449     450
Issuance of ADSs upon exercise of share options (in shares) 30,074        
Issuance of ADSs upon vesting of restricted share units (in shares) 35,000        
Share-based compensation expense   10,198     10,198
Foreign currency translation adjustment     920   920
Net loss       (27,564) (27,564)
Ending balance at Mar. 31, 2022 $ 385 578,284 (2,468) (245,943) 330,258
Ending balance (in shares) at Mar. 31, 2022 29,644,438        
Beginning balance at Dec. 31, 2022 $ 387 601,105 387 (331,096) $ 270,783
Beginning balance (in shares) at Dec. 31, 2022 29,873,893       29,873,893
Increase (decrease) in shareholders' equity (deficit)          
Issuance of ADSs upon exercise of share options   1     $ 1
Issuance of ADSs upon exercise of share options (in shares) 877        
Issuance of ADSs, net of commissions and offering expenses $ 1 2,715     2,716
Issuance of ADSs, net of commissions and offering expenses (in shares) 100,000        
Issuance of ADSs upon vesting of restricted share units $ 1       1
Issuance of ADSs upon vesting of restricted share units (in shares) 56,988        
Share-based compensation expense   9,042     9,042
Foreign currency translation adjustment     (316)   (316)
Net loss       (39,064) (39,064)
Ending balance at Mar. 31, 2023 $ 389 $ 612,863 $ 71 $ (370,160) $ 243,163
Ending balance (in shares) at Mar. 31, 2023 30,031,758       30,031,758