Accrued expenses and other current liabilities (Details) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Accrued expenses and other current liabilities
Accrued employee compensation and benefits	$ 4,380	$ 9,928
Accrued external research and development expenses	11,646	10,859
Accrued professional fees	1,436	1,068
Current portion of operating lease liabilities	4,655	3,125
Accrued income tax	$ 2,459	$ 970
Operating Lease, Liability, Current, Statement of Financial Position [Extensible List]	Accrued expenses and other current liabilities	Accrued expenses and other current liabilities
Other	$ 636	$ 502
Accrued expenses and other current liabilities	$ 25,212	$ 26,452