Property and equipment, net (Details) - USD ($) $ in Thousands	12 Months Ended
Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Property and equipment, net
Property and equipment, gross	$ 26,973	$ 7,923
Less: Accumulated depreciation and amortization	(7,863)	(4,800)
Property and equipment, net	19,110	3,123
Depreciation expense	3,700	1,400	$ 1,300
Laboratory equipment
Property and equipment, net
Property and equipment, gross	14,872	6,746
Laboratory equipment was not yet placed in service	2,300
Leasehold improvements
Property and equipment, net
Property and equipment, gross	10,736	809
Computer equipment and software
Property and equipment, net
Property and equipment, gross	441	143
Furniture and office equipment
Property and equipment, net
Property and equipment, gross	$ 924	$ 225

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount of structure or a modification to a structure under construction. Includes recently completed structures or modifications to structures that have not been placed into service.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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Amount after accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business to produce goods and services and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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