Summary of significant accounting policies - Property and equipment (Details)	12 Months Ended
	Dec. 31, 2022
Computer equipment and software
Property and equipment
Estimated Useful Life	3 years
Minimum | Laboratory equipment
Property and equipment
Estimated Useful Life	3 years
Minimum | Furniture and office equipment
Property and equipment
Estimated Useful Life	3 years
Maximum | Laboratory equipment
Property and equipment
Estimated Useful Life	5 years
Maximum | Furniture and office equipment
Property and equipment
Estimated Useful Life	5 years