Condensed Consolidated Statements of Shareholders' Equity - USD ($) $ in Thousands	Ordinary Shares	Additional Paid-in Capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit	Total
Beginning balance at Dec. 31, 2020	$ 266	$ 249,947	$ (3,193)	$ (151,560)	$ 95,460
Beginning balance (in shares) at Dec. 31, 2020	21,094,557
Increase (decrease) in shareholders' equity (deficit)
Issuance of ADSs upon exercise of share options	$ 1	283			284
Issuance of ADSs upon exercise of share options (in shares)	63,545
Issuance of ADSs, net of commissions and offering expenses	$ 33	58,742			58,775
Issuance of ADSs, net of commissions and offering expenses (in shares)	2,358,485
Share-based compensation expense		3,821			3,821
Foreign currency translation adjustment			(58)		(58)
Net loss				(16,191)	(16,191)
Ending balance at Mar. 31, 2021	$ 300	312,793	(3,251)	(167,751)	142,091
Ending balance (in shares) at Mar. 31, 2021	23,516,587
Beginning balance at Dec. 31, 2021	$ 384	567,637	(3,388)	(218,379)	$ 346,254
Beginning balance (in shares) at Dec. 31, 2021	29,579,364				29,579,364
Increase (decrease) in shareholders' equity (deficit)
Issuance of ADSs upon exercise of share options	$ 1	449			$ 450
Issuance of ADSs upon exercise of share options (in shares)	30,074
Issuance of ADSs upon vesting of restricted share units (in shares)	35,000
Share-based compensation expense		10,198			10,198
Foreign currency translation adjustment			920		920
Net loss				(27,564)	(27,564)
Ending balance at Mar. 31, 2022	$ 385	$ 578,284	$ (2,468)	$ (245,943)	$ 330,258
Ending balance (in shares) at Mar. 31, 2022	29,644,438				29,644,438