Nature of the business and basis of presentation - Liquidity (Details) - USD ($) $ in Thousands	3 Months Ended
Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021
Nature of the business and basis of presentation
Cash and cash equivalents	$ 407,371		$ 438,680
Net loss	27,564	$ 16,191
Accumulated deficit	$ 245,943		$ 218,379

The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

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+ Details

- Definition

The cumulative amount of the reporting entity's undistributed earnings or deficit.

+ References + Details