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Share-based compensation (Details) - shares
1 Months Ended 12 Months Ended
Jun. 30, 2020
May 31, 2019
Dec. 31, 2021
Jan. 01, 2022
Dec. 31, 2020
Stock option          
Share-based compensation.          
Shares outstanding 3,654,012   4,603,486   3,736,663
Employee Share Purchase Plan          
Share-based compensation.          
Percentage of annual increase in reserves on total number of ordinary shares outstanding   1.00%      
Number of ordinary shares reserved for issuance   215,000   295,793  
Number of shares available for issuance   430,000      
Percentage of ordinary shares at a price per share equal to the fair market value on offering date or purchase date   85.00%      
Increase in number of ordinary shares reserved for issuance     605,882    
2020 Plan          
Share-based compensation.          
Number of shares reserved for issuance 4,773,557   5,052,993    
Shares issued (in shares) 574,679        
Shares outstanding     1,780,353    
Percentage of annual increase in reserves on total number of ordinary shares outstanding 5.00%        
2020 Plan | Stock option          
Share-based compensation.          
Contractual life 10 years        
Number of shares reserved for issuance       1,478,968  
2020 Plan | Stock option | Non-employee Director          
Share-based compensation.          
Vesting period 3 years        
2020 Plan | Stock option | First anniversary          
Share-based compensation.          
Vesting Percentage 25.00%        
2020 Plan | Stock option | 36 equal monthly installments          
Share-based compensation.          
Number of equal monthly installments for vesting remaining awards 36 months        
2020 Plan | Stock option | Employee          
Share-based compensation.          
Vesting period 4 years        
2019 Plan          
Share-based compensation.          
Number of shares reserved for issuance 544,866        
2019 Plan | Stock option          
Share-based compensation.          
Shares outstanding     2,200,486    
Pre-IPO Share Options and restricted shares | Stock option          
Share-based compensation.          
Contractual life     10 years    
Pre-IPO Share Options and restricted shares | Stock option | First anniversary          
Share-based compensation.          
Vesting Percentage     25.00%    
Pre-IPO Share Options and restricted shares | Stock option | 36 equal monthly installments          
Share-based compensation.          
Number of equal monthly installments for vesting remaining awards     36 months    
Pre-IPO Share Options and restricted shares | Minimum | Stock option          
Share-based compensation.          
Vesting period     3 years    
Pre-IPO Share Options and restricted shares | Maximum | Stock option          
Share-based compensation.          
Vesting period     4 years