Net loss per share (Tables)

12 Months Ended

Dec. 31, 2021

Net loss per share

Schedule of basic and diluted net loss attributable to ordinary shareholders

Basic and diluted net loss per share was calculated as follows (in thousands, except share and per share amounts):

	Year Ended
	December 31,
	2021		2020		2019
Numerator:
Net loss	$	(66,819)	$	(51,010)	$	(30,608)
Denominator:
Weighted average ordinary shares outstanding, basic and diluted		25,061,734		19,145,938		11,045,370
Net loss per share, basic and diluted	$	(2.67)	$	(2.66)	$	(2.77)

Schedule of antidilutive securities excluded from computation of diluted net loss per share

	Year Ended
	December 31,
	2021	2020	2019
Warrants to subscribe for ordinary shares (1)	—	—	92,885
Options to purchase ordinary shares	4,603,486	3,736,663	2,634,346
	4,603,486	3,736,663	2,727,231

(1) At December 31, 2019, 65,000 warrants exercisable into 92,885 ordinary shares were outstanding (Note 8).