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Significant agreements - Genentech Collaboration Agreement (Details)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Feb. 21, 2020
USD ($)
item
May 31, 2018
USD ($)
Sep. 30, 2021
USD ($)
Sep. 30, 2020
USD ($)
Sep. 30, 2021
USD ($)
item
Sep. 30, 2020
USD ($)
Mar. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Significant agreements.                  
Option fee for development and exploitation rights   $ 5,000              
Collaboration revenues     $ 4,333 $ 3,842 $ 7,926 $ 6,542      
Deferred revenue     62,507   62,507     $ 35,156 $ 5,657
Genentech                  
Significant agreements.                  
Number of potential development candidates | item 4                
Upfront cash payment $ 30,000                
Number of immuno oncology targets | item 2                
Additional number of immuno oncology targets | item 2                
Expansion Fee $ 10,000                
Sales milestone payments, receivable             $ 2,000    
Transaction price 31,000   33,000   $ 33,000   $ 33,000    
Option fee for development and exploitation rights 30,000                
Period over which performance obligations will be performed         2 years        
Material rights exercise period         4 years        
Collaboration revenues     1,063 $ 1,209 $ 4,142 $ 3,066      
Deferred revenue     25,090   $ 25,090     $ 27,579 $ 0
Genentech | Royalty                  
Significant agreements.                  
Number of years over which royalty is payable         10 years        
Genentech | Maximum                  
Significant agreements.                  
Sales milestone payments, receivable 200,000                
Genentech | Development milestone | Maximum                  
Significant agreements.                  
Sales milestone payments, receivable 65,000                
Genentech | Regulatory milestone | Maximum                  
Significant agreements.                  
Sales milestone payments, receivable $ 135,000                
Genentech | Collaboration Program 1 Performance Obligation                  
Significant agreements.                  
Transaction price     4,019   $ 4,019        
Genentech | Collaboration Program 2 Performance Obligation                  
Significant agreements.                  
Transaction price     8,037   8,037        
Genentech | Specified Targeting Arm Material Right Arm Program One                  
Significant agreements.                  
Number of initial collaboration programs exercised | item 1                
Sales milestone payments, receivable $ 1,000                
Transaction price     352   $ 352        
Genentech | Two material rights associated with the LSR Go Option for Collaboration Programs One And Two                  
Significant agreements.                  
Number of expansion option collaboration programs | item         2        
Number of collaboration programs | item 2       2        
Transaction price     12,400   $ 12,400        
Genentech | Material rights for associated and limited substitution rights                  
Significant agreements.                  
Transaction price     1,187   1,187        
Genentech | Two material rights for Expansion Options                  
Significant agreements.                  
Number of expansion option collaboration programs | item 2                
Transaction price     $ 7,005   $ 7,005        
Genentech | Collaboration Program One and Two Performance Obligation | Maximum                  
Significant agreements.                  
Regulatory, and initial commercialization milestones, payments receivable $ 200,000