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Property and equipment, net (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Dec. 31, 2020
Property and equipment, net          
Property and equipment, gross $ 7,166   $ 7,166   $ 6,349
Less: Accumulated depreciation and amortization (4,729)   (4,729)   (4,032)
Property and equipment, net 2,437   2,437   2,317
Depreciation expense 300 $ 300 1,000 $ 900  
Laboratory equipment          
Property and equipment, net          
Property and equipment, gross 6,423   6,423   5,583
Leasehold improvements          
Property and equipment, net          
Property and equipment, gross 380   380   383
Computer equipment and software          
Property and equipment, net          
Property and equipment, gross 143   143   188
Furniture and office equipment          
Property and equipment, net          
Property and equipment, gross $ 220   $ 220   $ 195