Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Sep. 30, 2021	Dec. 31, 2020
Current assets:
Cash	$ 259,524	$ 135,990
Accounts receivable		5,456
Prepaid expenses and other current assets	5,644	5,100
Research and development incentives receivable	7,704	9,177
Total current assets	272,872	155,723
Property and equipment, net	2,437	2,317
Operating lease right-of-use assets	3,246	1,290
Other assets	2,778	1,822
Total assets	281,333	161,152
Current liabilities:
Accounts payable	1,761	1,365
Accrued expenses and other current liabilities	10,953	11,629
Deferred revenue, current portion	17,463	10,135
Total current liabilities	30,177	23,129
Long-term debt, net of discount	29,753	14,505
Operating lease liabilities, net of current portion	2,495	426
Deferred revenue, net of current portion	45,044	25,021
Other long-term liabilities	3,041	2,611
Total liabilities	110,510	65,692
Commitments and contingencies (Note 11)
Shareholders' equity:
Ordinary shares, 0.01 nominal value; 55,295,420 and 31,995,653 shares authorized at September 30, 2021 and December 31, 2020, respectively; 25,595,326 and 21,094,557 shares issued and outstanding at September 30, 2021 and December 31, 2020, respectively	329	266
Additional paid-in capital	374,029	249,947
Accumulated other comprehensive loss	(3,193)	(3,193)
Accumulated deficit	(200,342)	(151,560)
Total shareholders' equity	170,823	95,460
Total liabilities and shareholders' equity	$ 281,333	$ 161,152