Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2021	Dec. 31, 2020
Current assets:
Cash	$ 198,738	$ 135,990
Accounts receivable		5,456
Prepaid expenses and other current assets	4,792	5,100
Research and development incentives receivable	14,258	9,177
Total current assets	217,788	155,723
Property and equipment, net	2,353	2,317
Operating lease right-of-use assets	3,528	1,290
Other assets	2,379	1,822
Total assets	226,048	161,152
Current liabilities:
Accounts payable	3,471	1,365
Accrued expenses and other current liabilities	11,063	11,629
Deferred revenue, current portion	8,739	10,135
Total current liabilities	23,273	23,129
Long-term debt, net of discount	29,628	14,505
Operating lease liabilities, net of current portion	2,801	426
Deferred revenue, net of current portion	25,335	25,021
Other long-term liabilities	2,961	2,611
Total liabilities	83,998	65,692
Commitments and contingencies (Note 11)
Shareholders' equity:
Ordinary shares, 0.01 nominal value; 55,295,420 and 31,995,653 shares authorized at June 30, 2021 and December 31, 2020, respectively; 24,124,552 and 21,094,557 shares issued and outstanding at June 30, 2021 and December 31, 2020, respectively	309	266
Additional paid-in capital	330,911	249,947
Accumulated other comprehensive loss	(3,506)	(3,193)
Accumulated deficit	(185,664)	(151,560)
Total shareholders' equity	142,050	95,460
Total liabilities and shareholders' equity	$ 226,048	$ 161,152