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Net loss per share - Securities excluded from the diluted per share calculation (Details) - shares
3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Antidilutive securities    
Antidilutive securities (in shares) 4,950,608 3,726,338
Warrants to subscribe for convertible preferred shares (as adjusted to reflect the impact of the share capital reorganization and issuance of bonus shares    
Antidilutive securities    
Antidilutive securities (in shares) 50,000 71,450
Remaining warrants exercisable 71,450  
Options to purchase ordinary shares    
Antidilutive securities    
Antidilutive securities (in shares) 4,950,608 3,654,888