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Net loss per share per share - Securities excluded from the diluted per share calculation (Details) - shares
12 Months Ended
Mar. 07, 2019
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Antidilutive securities          
Antidilutive securities (in shares)   3,736,663 2,727,231 13,828,271  
Remaining warrants exercisable         80,000
Convertible preferred shares (as converted to ordinary shares)          
Antidilutive securities          
Antidilutive securities (in shares)       11,532,659  
Warrants to subscribe for convertible preferred shares (as adjusted to reflect the impact of the share capital reorganization and issuance of bonus shares          
Antidilutive securities          
Antidilutive securities (in shares)     92,885 1,347,953  
Percentage of warrants exercise in conjunction with IPO 50.00%        
Percentage of warrants expire 50.00%        
Remaining warrants exercisable     65,000    
Restricted ordinary shares          
Antidilutive securities          
Antidilutive securities (in shares)       83,947  
Options to purchase ordinary shares          
Antidilutive securities          
Antidilutive securities (in shares)   3,736,663 2,634,346 863,712  
Number of ordinary shares for warrants exercise     92,885