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Share-based compensation (Details)
1 Months Ended 12 Months Ended
Jan. 01, 2020
shares
Jun. 30, 2020
shares
May 31, 2019
shares
Dec. 31, 2020
$ / shares
shares
Dec. 31, 2018
Dec. 31, 2017
Jan. 01, 2021
shares
Dec. 31, 2019
$ / shares
shares
May 27, 2019
£ / shares
Subsequent events                  
Share-based compensation.                  
Number of ordinary shares reserved for issuance             210,945    
Stock option                  
Share-based compensation.                  
Shares outstanding   3,654,012   3,736,663       2,634,346  
Exercise price | $ / shares       $ 10.51       $ 9.57  
Employee Share Purchase Plan                  
Share-based compensation.                  
Percentage of annual increase in reserves on total number of ordinary shares outstanding     1.00%            
Increase in number of ordinary shares reserved for issuance 394,937                
Number of ordinary shares reserved for issuance     215,000            
Number of shares available for issuance     430,000            
Percentage of ordinary shares at a price per share equal to the fair market value on offering date or purchase date     85.00%            
2020 Plan                  
Share-based compensation.                  
Number of shares reserved for issuance   4,773,557   4,699,470          
Shares issued (in shares)   574,679              
Shares outstanding       196,550          
Percentage of annual increase in reserves on total number of ordinary shares outstanding   5.00%              
2020 Plan | Stock option                  
Share-based compensation.                  
Contractual life   10 years              
Increase in number of ordinary shares reserved for issuance       1,054,727          
2020 Plan | Stock option | Non-employee Director                  
Share-based compensation.                  
Vesting period   3 years              
2020 Plan | Stock option | First anniversary                  
Share-based compensation.                  
Vesting Percentage   25.00%              
2020 Plan | Stock option | 36 equal monthly installments                  
Share-based compensation.                  
Number of equal monthly installments for vesting remaining awards   36 months              
2020 Plan | Stock option | Employee                  
Share-based compensation.                  
Vesting period   4 years              
2019 Plan                  
Share-based compensation.                  
Number of shares reserved for issuance   544,866              
2019 Plan | Stock option                  
Share-based compensation.                  
Shares outstanding       2,594,277          
Pre-IPO Share Options and restricted shares | Stock option                  
Share-based compensation.                  
Contractual life       10 years          
Vesting period       4 years          
Pre-IPO Share Options and restricted shares | Stock option | First anniversary                  
Share-based compensation.                  
Vesting Percentage       25.00%          
Pre-IPO Share Options and restricted shares | Stock option | 36 equal monthly installments                  
Share-based compensation.                  
Number of equal monthly installments for vesting remaining awards       36 months          
Pre-IPO Share Options and restricted shares | Stock option | United Kingdom                  
Share-based compensation.                  
Exercise price | £ / shares                 £ 0.01
Pre-IPO Share Options and restricted shares | Performance based option | First anniversary                  
Share-based compensation.                  
Vesting Percentage         20.00% 20.00%      
Pre-IPO Share Options and restricted shares | Performance based option | 36 equal monthly installments                  
Share-based compensation.                  
Vesting Percentage         60.00% 60.00%      
Number of equal monthly installments for vesting remaining awards         36 months 36 months      
Pre-IPO Share Options and restricted shares | Performance based option | Earlier of the fourth anniversary                  
Share-based compensation.                  
Vesting Percentage         20.00% 20.00%      
Pre-IPO Share Options and restricted shares | Minimum | Stock option                  
Share-based compensation.                  
Vesting period       3 years          
Pre-IPO Share Options and restricted shares | Maximum | Stock option                  
Share-based compensation.                  
Vesting period       4 years