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Consolidated Statements of Convertible Preferred Shares and Shareholders’ Equity (Deficit) - USD ($)
$ in Thousands
Series A Convertible Preferred Shares
Series B1 Convertible Preferred Shares
Series B2 Convertible Preferred Shares
Ordinary Shares
Additional Paid-in Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Total
Beginning balance at Dec. 31, 2017 $ 41,820 $ 54,621            
Beginning balance (in shares) at Dec. 31, 2017 2,800,001 3,947,198            
Increase (decrease) in convertible preferred shares                
Issuance of convertible preferred shares     $ 25,756          
Issuance of convertible preferred shares (in shares)     1,323,248          
Ending balance at Dec. 31, 2018 $ 41,820 $ 54,621 $ 25,756          
Ending balance (in shares) at Dec. 31, 2018 2,800,001 3,947,198 1,323,248          
Beginning balance at Dec. 31, 2017       $ 5 $ 838 $ 69 $ (48,096) $ (47,184)
Beginning balance (in shares) at Dec. 31, 2017       368,995        
Increase (decrease) in shareholders' equity (deficit)                
Issuance of restricted share awards       $ 1 223     224
Issuance of restricted share awards (in shares)       95,644        
Issuance of ordinary shares in exchange for surrender of vested share options       $ 4 (4)      
Issuance of ordinary shares in exchange for surrender of vested share options (in shares)       340,728        
Issuance of ordinary shares upon exercise of share options (in shares)       9,361        
Share based compensation expense         800     800
Foreign currency translation adjustment           (1,820)   (1,820)
Net loss             (21,846) (21,846)
Ending balance at Dec. 31, 2018       $ 10 1,857 (1,751) (69,942) (69,826)
Ending balance (in shares) at Dec. 31, 2018       814,728        
Increase (decrease) in convertible preferred shares                
Issuance of convertible preferred shares     $ 1,583          
Issuance of convertible preferred shares (in shares)     80,385          
Conversion of convertible preferred shares to ordinary shares $ (41,820) $ (54,621) $ (27,339)          
Conversion of convertible preferred shares to ordinary shares (in shares) (2,800,001) (3,947,198) (1,403,633)          
Increase (decrease) in shareholders' equity (deficit)                
Reclassification of warrant liability to additional paid-in capital and exercise of warrants       $ 9 10,018     10,027
Reclassification of warrant liability to additional paid-in capital and exercise of warrants (in shares)       723,992        
Conversion of convertible preferred shares to ordinary shares       $ 146 123,634     123,780
Conversion of convertible preferred shares to ordinary shares (in shares)       11,647,529        
Issuance of ADSs in initial public offering, net of underwriting discounts, commissions and offering expenses       $ 59 56,322     56,381
Issuance of ADSs in initial public offering, net of underwriting discounts, commissions and offering expenses (in shares)       4,637,666        
Issuance of restricted share awards       $ 2 395     397
Issuance of restricted share awards (in shares)       83,947        
Issuance of ordinary shares upon exercise of share options       $ 1 142     143
Issuance of ordinary shares upon exercise of share options (in shares)       85,839        
Share based compensation expense         2,688     2,688
Foreign currency translation adjustment           216   216
Net loss             (30,608) (30,608)
Ending balance at Dec. 31, 2019       $ 227 195,056 (1,535) (100,550) $ 93,198
Ending balance (in shares) at Dec. 31, 2019       17,993,701       17,993,701
Increase (decrease) in shareholders' equity (deficit)                
Issuance of ordinary shares upon exercise of warrants       $ 1       $ 1
Issuance of ordinary shares upon exercise of warrants (in shares)       92,885        
Issuance of ADSs in initial public offering, net of underwriting discounts, commissions and offering expenses       $ 37 48,107     48,144
Issuance of ADSs in initial public offering, net of underwriting discounts, commissions and offering expenses (in shares)       2,928,813        
Issuance of ordinary shares upon exercise of share options       $ 1 270     271
Issuance of ordinary shares upon exercise of share options (in shares)       79,158        
Share based compensation expense         6,514     6,514
Foreign currency translation adjustment           (1,658)   (1,658)
Net loss             (51,010) (51,010)
Ending balance at Dec. 31, 2020       $ 266 $ 249,947 $ (3,193) $ (151,560) $ 95,460
Ending balance (in shares) at Dec. 31, 2020       21,094,557       21,094,557