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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Consolidated Statements of Operations and Comprehensive Loss      
Collaboration revenues $ 10,390 $ 13,801 $ 7,136
Operating expenses:      
Research and development 33,149 25,540 20,761
General and administrative 29,201 14,560 8,121
Total operating expenses 62,350 40,100 28,882
Loss from operations (51,960) (26,299) (21,746)
Other income (expense):      
Interest income 683 814 169
Interest expense (457)    
Other expense, net   (5,377) (665)
Total other income (expense), net 226 (4,563) (496)
Net loss before income tax provision (51,734) (30,862) (22,242)
(Benefit from) provision for income taxes (724) (254) (396)
Net loss (51,010) (30,608) (21,846)
Net loss attributable to ordinary shareholders $ (51,010) $ (30,608) $ (21,846)
Net loss per share attributable to ordinary shareholders, basic and diluted $ (2.66) $ (2.77) $ (49.78)
Weighted average ordinary shares outstanding, basic and diluted 19,145,938 11,045,370 438,862
Comprehensives Loss:      
Net loss $ (51,010) $ (30,608) $ (21,846)
Other comprehensive income (loss):      
Foreign currency translation adjustment (1,658) 216 (1,820)
Total comprehensive loss $ (52,668) $ (30,392) $ (23,666)