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Property and equipment, net (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Dec. 31, 2019
Property and equipment, net          
Property and equipment, gross $ 5,535   $ 5,535   $ 4,975
Less: Accumulated depreciation and amortization (3,496)   (3,496)   (2,683)
Property and equipment, net 2,039   2,039   2,292
Depreciation expense 300 $ 200 900 $ 700  
Laboratory equipment          
Property and equipment, net          
Property and equipment, gross 4,790   4,790   4,326
Leasehold improvements          
Property and equipment, net          
Property and equipment, gross 371   371   300
Computer equipment and software          
Property and equipment, net          
Property and equipment, gross 185   185   229
Furniture and office equipment          
Property and equipment, net          
Property and equipment, gross $ 189   $ 189   $ 120