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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Condensed Consolidated Statements of Operations and Comprehensive Loss        
Collaboration revenues $ 3,842 $ 614 $ 6,542 $ 8,520
Operating expenses:        
Research and development 7,363 6,078 23,091 18,891
General and administrative 7,154 4,789 18,351 11,164
Total operating expenses 14,517 10,867 41,442 30,055
Loss from operations (10,675) (10,253) (34,900) (21,535)
Other income (expense):        
Interest and other income, net 72 440 655 594
Other expense, net       (5,377)
Total other income (expense), net 72 440 655 (4,783)
Net loss before income tax provision (10,603) (9,813) (34,245) (26,318)
Benefit from income taxes (465) (331) (668) (116)
Net loss (10,138) (9,482) (33,577) (26,202)
Net loss attributable to ordinary shareholders $ (10,138) $ (9,482) $ (33,577) $ (26,202)
Net loss per share attributable to ordinary shareholders, basic and diluted $ (0.52) $ (0.53) $ (1.81) $ (3.00)
Weighted average ordinary shares outstanding, basic and diluted 19,426,833 17,900,978 18,504,013 8,734,943
Comprehensives Loss:        
Net loss $ (10,138) $ (9,482) $ (33,577) $ (26,202)
Other comprehensive income (loss):        
Foreign currency translation adjustment 743 (424) (1,442) (856)
Total comprehensive loss $ (9,395) $ (9,906) $ (35,019) $ (27,058)