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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Cash flows from operating activities:    
Net loss $ (23,438) $ (16,720)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:    
Share-based compensation expense 3,440 1,181
Depreciation and amortization 615 443
Change in fair value of warrant liability 0 5,381
Changes in operating assets and liabilities:    
Accounts receivable (332) 4,955
Research and development incentives receivable (4,446) (3,518)
Prepaid expenses and other current assets 267 (60)
Operating lease right-of-use assets 374 352
Other assets (292) (124)
Accounts payable 1,325 530
Accrued expenses and other current liabilities 2,050 (978)
Lease liabilities 4 (351)
Deferred revenue 29,013 (4,329)
Other long-term liabilities 233 429
Net cash provided by (used in) operating activities 8,813 (12,809)
Cash used in investing activities:    
Purchases of property and equipment (621) (881)
Net cash used in investing activities (621) (881)
Cash flows from financing activities:    
Proceeds from the issuance of ADSs in initial public offering, net of issuance costs   57,768
Proceeds from the exercise of share options and sale of ordinary shares 11 21
Proceeds from the exercise of warrants 1 6
Net cash provided by financing activities 12 59,129
Effect of exchange rate changes on cash (3,411) (283)
Net increase in cash 4,793 45,156
Cash at beginning of period 92,117 63,380
Cash at end of period 96,910 108,536
Supplemental disclosure of cash flow information    
Cash paid for income taxes 38 73
Public offering costs accrued but not paid 274 664
Cash paid for amounts included in the measurement of operating lease liabilities 406 447
Purchases of property and equipment included in accounts payable and accrued expenses $ 12  
Conversion of convertible preferred shares to ordinary shares upon closing of the initial public offering   123,780
Reclassification of warrant liability to additional paid-in capital   10,021
Series B2 Convertible Preferred Shares    
Cash flows from financing activities:    
Proceeds from issuance of convertible preferred shares, net of issuance costs   $ 1,334