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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Cash flows from operating activities:    
Net loss $ (11,324) $ (6,503)
Adjustments to reconcile net loss to net cash used in operating activities:    
Share-based compensation expense 2,121 276
Depreciation and amortization 305 213
Change in fair value of warrant liability 0 3,197
Changes in operating assets and liabilities:    
Accounts receivable (846) 4,860
Research and development incentives receivable (2,097) (1,650)
Prepaid expenses and other current assets 347 (215)
Operating lease right-of-use assets 187 176
Other assets (215) 125
Accounts payable 2,702 415
Accrued expenses and other current liabilities (464) (783)
Lease liabilities 191 (176)
Deferred revenue 30,103 (5,327)
Other long-term liabilities 152 191
Net cash provided by (used in) operating activities 21,162 (5,201)
Cash used in investing activities:    
Purchases of property and equipment (320) (418)
Net cash used in investing activities (320) (418)
Cash flows from financing activities:    
Payments of initial public offering costs   (1,300)
Proceeds from the exercise of share options and sale of ordinary shares 2  
Net cash provided by financing activities 2 34
Effect of exchange rate changes on cash (3,324) 1,569
Net increase (decrease) in cash 17,520 (4,016)
Cash at beginning of period 92,117 63,380
Cash at end of period 109,637 59,364
Supplemental disclosure of cash flow information    
Cash paid for income taxes 11  
Cash paid for amounts included in the measurement of operating lease liabilities   224
Purchases of property and equipment included in accounts payable and accrued expenses $ 71  
Deferred initial public offering costs accrued but not paid   431
Series B2 Convertible Preferred Shares    
Cash flows from financing activities:    
Proceeds from issuance of convertible preferred shares, net of issuance costs   $ 1,334