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Significant agreements - Cancer Research UK (Details) - USD ($)
$ in Millions
1 Months Ended
Dec. 13, 2016
Dec. 31, 2019
Dec. 31, 2018
Research and development arrangement obligation to repay other parties      
Contingent future milestones payments under research and development arrangement $ 50.9 $ 60.3  
Other long term liabilities      
Research and development arrangement obligation to repay other parties      
Liability from research and development   $ 2.0 $ 0.8
Commercialization license per candidate      
Research and development arrangement obligation to repay other parties      
Refunding the costs and expenses incurred in case of termination (as a percent) 50.00%    
BT1718 | Minimum      
Research and development arrangement obligation to repay other parties      
Tiered royalties (percentage) 70.00%    
BT1718 | Maximum      
Research and development arrangement obligation to repay other parties      
Tiered royalties (percentage) 90.00%    
BT7401 | Minimum      
Research and development arrangement obligation to repay other parties      
Tiered royalties (percentage)   55.00%  
BT7401 | Maximum      
Research and development arrangement obligation to repay other parties      
Tiered royalties (percentage)   80.00%