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Nature of the business and basis of presentation- Liquidity (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Nature of business and basis of presentation                      
Net loss $ 4,406 $ 9,482 $ 10,217 $ 6,503 $ 6,641 $ 7,692 $ 4,979 $ 2,534 $ 30,608 $ 21,846 $ 16,259
Accumulated deficit $ 100,550       $ 69,942       $ 100,550 $ 69,942