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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Condensed Consolidated Statements of Operations and Comprehensive Loss        
Collaboration revenues $ 614 $ 1,610 $ 8,520 $ 6,079
Operating expenses:        
Research and development 6,078 5,642 18,891 14,268
General and administrative 4,789 2,325 11,164 6,015
Total operating expenses 10,867 7,967 30,055 20,283
Loss from operations (10,253) (6,357) (21,535) (14,204)
Other income (expense):        
Interest and other income 440 26 594 75
Other expense, net   (1,361) (5,377) (1,472)
Total other income (expense), net 440 (1,335) (4,783) (1,397)
Net loss before income tax provision (9,813) (7,692) (26,318) (15,601)
Benefit from income taxes (331) 0 (116) (396)
Net loss (9,482) (7,692) (26,202) (15,205)
Net loss attributable to ordinary shareholders $ (9,482) $ (7,692) $ (26,202) $ (15,205)
Net loss per share attributable to ordinary shareholders, basic and diluted $ (0.53) $ (17.73) $ (3.00) $ (36.44)
Weighted average ordinary shares outstanding, basic and diluted 17,900,978 433,795 8,734,943 417,223
Comprehensives Loss:        
Net loss $ (9,482) $ (7,692) $ (26,202) $ (15,205)
Other comprehensive income (loss):        
Foreign currency translation adjustment (424) (537) (856) (1,398)
Total comprehensive loss $ (9,906) $ (8,229) $ (27,058) $ (16,603)