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Nature of the business and basis of presentation- Liquidity (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Sep. 30, 2019
Sep. 30, 2018
Dec. 31, 2018
Nature of business and basis of presentation                  
Net loss $ 9,482 $ 10,217 $ 6,503 $ 7,692 $ 4,979 $ 2,534 $ 26,202 $ 15,205  
Accumulated deficit $ 96,144           $ 96,144   $ 69,942