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Subsequent events	9 Months Ended
Subsequent events	Sep. 30, 2019
Subsequent events
Subsequent events	17. Subsequent events Effective October 23, 2019, Sanofi terminated the Sanofi Collaboration Agreement. As a result, deferred revenue related to amounts allocated to the Hemophilia License Option Material Right of approximately $4.5 million will be recognized as collaboration revenue in the fourth quarter of 2019.