<SEC-DOCUMENT>0001193805-24-000665-index.html : 20240516
<SEC-HEADER>0001193805-24-000665.hdr.sgml : 20240516
<ACCEPTANCE-DATETIME>20240516172035
ACCESSION NUMBER:		0001193805-24-000665
CONFORMED SUBMISSION TYPE:	F-6EF
PUBLIC DOCUMENT COUNT:		12
FILED AS OF DATE:		20240516
DATE AS OF CHANGE:		20240516

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BICYCLE THERAPEUTICS plc
		CENTRAL INDEX KEY:			0001761612
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				000000000

	FILING VALUES:
		FORM TYPE:		F-6EF
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-279465
		FILM NUMBER:		24956818

	BUSINESS ADDRESS:	
		STREET 1:		BLOCKS A & B, PORTWAY BUILDING
		STREET 2:		GRANTA PARK, GREAT ABINGTON
		CITY:			CAMBRIDGE
		STATE:			X0
		ZIP:			CB21 6GS
		BUSINESS PHONE:		011441223261503

	MAIL ADDRESS:	
		STREET 1:		BLOCKS A & B, PORTWAY BUILDING
		STREET 2:		GRANTA PARK, GREAT ABINGTON
		CITY:			CAMBRIDGE
		STATE:			X0
		ZIP:			CB21 6GS

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BICYCLE THERAPEUTICS Ltd
		DATE OF NAME CHANGE:	20181212

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Citibank,N.A./ADR
		CENTRAL INDEX KEY:			0001472033
		ORGANIZATION NAME:           	International Corp Fin
		IRS NUMBER:				521568099
		STATE OF INCORPORATION:			DC
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		F-6EF

	BUSINESS ADDRESS:	
		STREET 1:		388 GREENWICH STREET, 14TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10013
		BUSINESS PHONE:		212-816-6647

	MAIL ADDRESS:	
		STREET 1:		388 GREENWICH STREET, 14TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10013
</SEC-HEADER>
<DOCUMENT>
<TYPE>F-6EF
<SEQUENCE>1
<FILENAME>e663625_f6ef-bt.htm
<TEXT>
Document 1 - file: e663625_f6ef-bt.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.(A)
<SEQUENCE>2
<FILENAME>e663625_ex99-a.htm
<TEXT>
Document 2 - file: e663625_ex99-a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.(B)(I)
<SEQUENCE>3
<FILENAME>e663625_ex99-bi.htm
<TEXT>
Document 3 - file: e663625_ex99-bi.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.(B)(II)
<SEQUENCE>4
<FILENAME>e663625_ex99-bii.htm
<TEXT>
Document 4 - file: e663625_ex99-bii.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.(B)(III)
<SEQUENCE>5
<FILENAME>e663625_ex99-biii.htm
<TEXT>
Document 5 - file: e663625_ex99-biii.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.(B)(IV)
<SEQUENCE>6
<FILENAME>e663625_ex99-biv.htm
<TEXT>
Document 6 - file: e663625_ex99-biv.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.(B)(V)
<SEQUENCE>7
<FILENAME>e663625_ex99-bv.htm
<TEXT>
Document 7 - file: e663625_ex99-bv.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.(D)
<SEQUENCE>8
<FILENAME>e663625_ex99-d.htm
<TEXT>
Document 8 - file: e663625_ex99-d.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.(E)
<SEQUENCE>9
<FILENAME>e663625_ex99-e.htm
<TEXT>
Document 9 - file: e663625_ex99-e.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>image.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 10 - file: image.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>image2.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 11 - file: image2.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>12
<FILENAME>image3.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 12 - file: image3.jpg

</DOCUMENT>
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