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Net loss per share - Basic and diluted net loss per share (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Numerator:        
Net loss attributable to ordinary shareholders $ (10,217) $ (4,979) $ (16,720) $ (7,513)
Denominator:        
Weighted average ordinary shares outstanding, basic and diluted 7,298,139 420,063 4,101,564 408,807
Net loss per share attributable to ordinary shareholders, basic and diluted $ (1.40) $ (11.85) $ (4.08) $ (18.38)