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Summary of significant accounting policies - Government grants (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Summary of significant accounting policies        
Reduction of research and development $ 0.1 $ 0.0 $ 0.2 $ 0.0