Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2019	Dec. 31, 2018
Current assets:
Cash	$ 108,536	$ 63,380
Accounts receivable	160	5,021
Prepaid expenses and other current assets	2,021	2,076
Research and development incentives receivable	9,735	6,292
Total current assets	120,452	76,769
Property and equipment, net	2,002	1,818
Operating lease right-of-use assets	2,386
Other assets	1,406	3,039
Total assets	126,246	81,626
Current liabilities:
Accounts payable	2,569	1,887
Accrued expenses and other current liabilities	5,859	7,032
Deferred revenue, current portion	1,012	10
Total current liabilities	9,440	8,929
Warrant liability		4,804
Deferred revenue, net of current portion	9,358	14,625
Long term lease liabilities	1,628
Other long-term liabilities	1,261	897
Total liabilities	21,687	29,255
Commitments and contingencies (Note 12)
Shareholders' equity (deficit):
Ordinary shares, 0.01 nominal value; 31,995,653 and 15,452,420 shares authorized at June 30, 2019 and December 31, 2018, respectively; 17,900,731 shares issued and outstanding at June 30, 2019, respectively; 898,678 shares issued and 814,728 shares outstanding at December 31, 2018 , respectively	226	10
Additional paid-in capital	193,178	1,857
Accumulated other comprehensive loss	(2,183)	(1,751)
Accumulated deficit	(86,662)	(69,942)
Total shareholders' equity (deficit)	104,559	(69,826)
Total liabilities, convertible preferred shares and shareholders' equity (deficit)	$ 126,246	81,626
Series A Convertible Preferred Shares
Current liabilities:
Convertible preferred shares		41,820
Series B1 Convertible Preferred Shares
Current liabilities:
Convertible preferred shares		54,621
Series B2 Convertible Preferred Shares
Current liabilities:
Convertible preferred shares		$ 25,756