<SEC-DOCUMENT>0001047469-20-002601-index.html : 20200427
<SEC-HEADER>0001047469-20-002601.hdr.sgml : 20200427
<ACCEPTANCE-DATETIME>20200427160232
ACCESSION NUMBER:		0001047469-20-002601
CONFORMED SUBMISSION TYPE:	DEF 14A
PUBLIC DOCUMENT COUNT:		7
CONFORMED PERIOD OF REPORT:	20200629
FILED AS OF DATE:		20200427
DATE AS OF CHANGE:		20200427
EFFECTIVENESS DATE:		20200427

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BICYCLE THERAPEUTICS plc
		CENTRAL INDEX KEY:			0001761612
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000

	FILING VALUES:
		FORM TYPE:		DEF 14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38916
		FILM NUMBER:		20819923

	BUSINESS ADDRESS:	
		STREET 1:		B900 BABRAHAM RESEARCH CAMPUS
		CITY:			CAMBRIDGE
		STATE:			X0
		ZIP:			CB22 3AT
		BUSINESS PHONE:		011441223261503

	MAIL ADDRESS:	
		STREET 1:		B900 BABRAHAM RESEARCH CAMPUS
		CITY:			CAMBRIDGE
		STATE:			X0
		ZIP:			CB22 3AT

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BICYCLE THERAPEUTICS Ltd
		DATE OF NAME CHANGE:	20181212
</SEC-HEADER>
<DOCUMENT>
<TYPE>DEF 14A
<SEQUENCE>1
<FILENAME>a2241418zdef14a.htm
<DESCRIPTION>DEF 14A
<TEXT>
Document 1 - file: a2241418zdef14a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>g159922bgi001.jpg
<DESCRIPTION>G159922BGI001.JPG
<TEXT>
Document 2 - file: g159922bgi001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>g159922bgi002.jpg
<DESCRIPTION>G159922BGI002.JPG
<TEXT>
Document 3 - file: g159922bgi002.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>g746790.jpg
<DESCRIPTION>G746790.JPG
<TEXT>
Document 4 - file: g746790.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>g965098.jpg
<DESCRIPTION>G965098.JPG
<TEXT>
Document 5 - file: g965098.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>g419268.jpg
<DESCRIPTION>G419268.JPG
<TEXT>
Document 6 - file: g419268.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>g638898.jpg
<DESCRIPTION>G638898.JPG
<TEXT>
Document 7 - file: g638898.jpg

</DOCUMENT>
</SEC-DOCUMENT>