<SEC-DOCUMENT>0001047469-19-003124-index.html : 20190515
<SEC-HEADER>0001047469-19-003124.hdr.sgml : 20190515
<ACCEPTANCE-DATETIME>20190515170802
ACCESSION NUMBER:		0001047469-19-003124
CONFORMED SUBMISSION TYPE:	S-1/A
PUBLIC DOCUMENT COUNT:		8
FILED AS OF DATE:		20190515
DATE AS OF CHANGE:		20190515

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BICYCLE THERAPEUTICS Ltd
		CENTRAL INDEX KEY:			0001761612
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000

	FILING VALUES:
		FORM TYPE:		S-1/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-231076
		FILM NUMBER:		19829502

	BUSINESS ADDRESS:	
		STREET 1:		B900 BABRAHAM RESEARCH CAMPUS
		CITY:			CAMBRIDGE
		STATE:			X0
		ZIP:			CB22 3AT
		BUSINESS PHONE:		011441223261503

	MAIL ADDRESS:	
		STREET 1:		B900 BABRAHAM RESEARCH CAMPUS
		CITY:			CAMBRIDGE
		STATE:			X0
		ZIP:			CB22 3AT
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<TYPE>S-1/A
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<DESCRIPTION>S-1/A
<TEXT>
Document 1 - file: a2238828zs-1a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.7
<SEQUENCE>2
<FILENAME>a2238828zex-10_7.htm
<DESCRIPTION>EX-10.7
<TEXT>
Document 2 - file: a2238828zex-10_7.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.8
<SEQUENCE>3
<FILENAME>a2238828zex-10_8.htm
<DESCRIPTION>EX-10.8
<TEXT>
Document 3 - file: a2238828zex-10_8.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.9
<SEQUENCE>4
<FILENAME>a2238828zex-10_9.htm
<DESCRIPTION>EX-10.9
<TEXT>
Document 4 - file: a2238828zex-10_9.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.10
<SEQUENCE>5
<FILENAME>a2238828zex-10_10.htm
<DESCRIPTION>EX-10.10
<TEXT>
Document 5 - file: a2238828zex-10_10.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.11
<SEQUENCE>6
<FILENAME>a2238828zex-10_11.htm
<DESCRIPTION>EX-10.11
<TEXT>
Document 6 - file: a2238828zex-10_11.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>g415402ls03i001.gif
<DESCRIPTION>G415402LS03I001.GIF
<TEXT>
Document 7 - file: g415402ls03i001.gif

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>g415402ls03i002.jpg
<DESCRIPTION>G415402LS03I002.JPG
<TEXT>
Document 8 - file: g415402ls03i002.jpg

</DOCUMENT>
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