<SEC-DOCUMENT>0000935836-22-000165-index.html : 20220214
<SEC-HEADER>0000935836-22-000165.hdr.sgml : 20220214
<ACCEPTANCE-DATETIME>20220214151641
ACCESSION NUMBER:		0000935836-22-000165
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20220214
DATE AS OF CHANGE:		20220214

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BICYCLE THERAPEUTICS plc
		CENTRAL INDEX KEY:			0001761612
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-91023
		FILM NUMBER:		22630330

	BUSINESS ADDRESS:	
		STREET 1:		B900 BABRAHAM RESEARCH CAMPUS
		CITY:			CAMBRIDGE
		STATE:			X0
		ZIP:			CB22 3AT
		BUSINESS PHONE:		011441223261503

	MAIL ADDRESS:	
		STREET 1:		B900 BABRAHAM RESEARCH CAMPUS
		CITY:			CAMBRIDGE
		STATE:			X0
		ZIP:			CB22 3AT

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BICYCLE THERAPEUTICS Ltd
		DATE OF NAME CHANGE:	20181212

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Logos Global Management LP
		CENTRAL INDEX KEY:			0001792126
		IRS NUMBER:				833997742
		STATE OF INCORPORATION:			CA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		1 LETTERMAN DRIVE
		STREET 2:		STE. D3-700
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94129
		BUSINESS PHONE:		4158014660

	MAIL ADDRESS:	
		STREET 1:		1 LETTERMAN DRIVE
		STREET 2:		STE. D3-700
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94129
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>bicycle13ga1.htm
<TEXT>
Document 1 - file: bicycle13ga1.htm

</DOCUMENT>
</SEC-DOCUMENT>